中文名稱: MRPL12 抗原(重組蛋白)
英文名稱: MRPL12 Antigen (Recombinant Protein)w
別 名: mitochondrial ribosomal protein L12; 5c5-2; L12mt; MRPL7; RPML12; MRPL7/L12; MRP-L31/34
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述
Fusion protein corresponding to a region derived from 46-198 amino acids of human MRPL12
技術(shù)規(guī)格
Full name:
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mitochondrial ribosomal protein L12
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Synonyms:
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5c5-2; L12mt; MRPL7; RPML12; MRPL7/L12; MRP-L31/34
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Swissprot:
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P52815
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Gene Accession:
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BC002344
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Purity:
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>85%, as determined by Coomassie blue stained SDS-PAGE
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Expression system:
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Escherichia coli
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Tags:
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His tag C-Terminus, GST tag N-Terminus
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Background:
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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.
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